Institute of Biomedicine, Research Area for Women's Health, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador.
Gynecol Endocrinol. 2013 Jun;29(6):563-8. doi: 10.3109/09513590.2013.788637.
Prevalence of the metabolic syndrome (METS) increases significantly after the menopause.
To assess the prevalence of the METS and its components in postmenopausal women. Factors relating to each of the composing items of the METS were also analyzed.
Natural postmenopausal women (40-65 years) were invited to participate in this cross-sectional study in order to assess the presence of the METS using modified Adult Treatment Panel III (ATP-III) criteria. Participants were also requested to fill out a general socio-demographic questionnaire.
A total of 204 women were surveyed with a median age of 56 years. A 52.9% presented the METS according to modified ATP-III criteria, with 37.3% presenting hyperglycemia, 51.5% hypertension, 58.3% abdominal obesity, 45.6% high triglyceride levels and 56.4% low HDL-C levels. Women with the METS presented a higher rate of dyslipidemia (high triglyceride and low HDL-C levels), hyperglycemia, hypertension and abdominal obesity than those without the syndrome. Those with abdominal obesity and hyperglycemia significantly displayed higher rates of low HDL-C levels (bivariate analysis). Multiple linear regression analysis found a positive correlation between glucose and triglyceride levels. Systolic blood pressure significantly and positively correlated to age and abdominal circumference. Abdominal circumference displayed an inverse correlation with educational level.
Prevalence of the METS in this postmenopausal female sample was high and associated to metabolic and lipid derangements. As abdominal obesity was significantly associated to lower education, there is an urgent need of implementing educational programs directed to high-risk populations in order to increase awareness of the problem.
代谢综合征（METS）在绝经后显著增加。
评估绝经后妇女 METS 的患病率及其各组成部分。还分析了与 METS 各组成部分相关的因素。
邀请自然绝经的女性（40-65 岁）参加这项横断面研究，以使用改良成人治疗小组 III（ATP-III）标准评估 METS 的存在。还要求参与者填写一份一般社会人口统计学问卷。
共有 204 名女性接受了调查，平均年龄为 56 岁。根据改良的 ATP-III 标准，52.9%的女性患有 METS，其中 37.3%存在高血糖，51.5%存在高血压，58.3%存在腹部肥胖，45.6%存在高甘油三酯水平，56.4%存在低高密度脂蛋白胆固醇水平。患有 METS 的女性比未患有该综合征的女性有更高的血脂异常（高甘油三酯和低高密度脂蛋白胆固醇水平）、高血糖、高血压和腹部肥胖发生率。腹部肥胖和高血糖的女性显著显示出更低的高密度脂蛋白胆固醇水平（双变量分析）。多元线性回归分析发现血糖和甘油三酯水平之间存在正相关。收缩压与年龄和腰围呈显著正相关。腰围与教育水平呈负相关。
在这个绝经后女性样本中，METS 的患病率较高，与代谢和脂质紊乱有关。由于腹部肥胖与较低的教育程度显著相关，因此迫切需要实施针对高危人群的教育计划，以提高对该问题的认识。
