Destombes P, Mariat F, Rosati L, Segretain G
Acta Trop. 1977 Dec;34(4):355-73.
The Pasteur Institute studied 103 mycetoma patients in Somalia between 1959 and 1964. Grains were seen in 94 of them and this, added to cultural features, allowed the diagnosis of 60 pathogens as follows: 44 Madurella mycetomi, 1 Leptosphaeria senegalensis, 7 Pyrenochaeta romeroi (or Madurella grisea), 3 Allescheria boydii, 1 Fusarium sp., 3 Neotestudina (Zopfia) rosatii, and 1 unidentified; 34 were actinomycetes: 24 Streptomyces somaliensis, 4 Actinomadura madurae, 3 A. pelletieri and 3 Nocardia spp. The patients delayed too long in consulting their doctors and health education is vital if amputations are to be avoided. The geographical distribution is related to climate and fungal species. In central Somalia the association of M. mycetomi and S. somaliensis, organisms characteristic of desert conditions, was found; white grain mycetomata and those caused by Nocardia spp. occurred in more humid areas. The study revealed 2 new fungi. One, obtained in culture was called Neotestudina (Zopfia) rosatii. The 3 patients affected, lived in Mudugh (2 in El Bur). The other fungus was not identified. It also was recovered from El Bur and one with similar microscopic characters has been seen in Chad and also in "territoire français des Afars et des Issas". Both fungi are desert species.
1959年至1964年间,巴斯德研究所对索马里的103名足菌肿患者进行了研究。其中94名患者可见颗粒,结合培养特征,确诊了60种病原体,具体如下:44例马杜拉足分支菌,1例塞内加尔细球壳菌,7例罗梅罗瓶霉(或灰马杜拉足分支菌),3例博伊德阿利什霉,1例镰孢菌属,3例罗氏新龟甲菌(或罗氏佐菲亚菌),1例未鉴定;34例放线菌:24例索马里链霉菌,4例马杜拉放线菌,3例佩氏放线菌和3例诺卡氏菌属。患者就医延迟时间过长,若要避免截肢,健康教育至关重要。地理分布与气候和真菌种类有关。在索马里中部,发现了马杜拉足分支菌和索马里链霉菌的组合,这两种菌是沙漠环境的特征菌;白色颗粒足菌肿和由诺卡氏菌属引起的足菌肿出现在湿度较大的地区。该研究发现了2种新真菌。一种通过培养获得,名为罗氏新龟甲菌(或罗氏佐菲亚菌)。受影响的3名患者居住在穆杜格(2例在布尔)。另一种真菌未鉴定。它也从布尔分离得到,在乍得以及“法属阿法尔和伊萨领地”也发现了具有相似微观特征的真菌。这两种真菌都是沙漠物种。