静脉注射葡萄糖对急性窒息血流动力学反应有益作用的证据。

Evidence for beneficial effect of intravenous glucose on the hemodynamic response to acute asphyxia.

作者信息

Scholle S F, Griggs D M

出版信息

Proc Soc Exp Biol Med. 1975 Mar;148(3):743-7. doi: 10.3181/00379727-148-38622.

Abstract

Anesthetized rabbits were subjected to two 4-min periods of asphyxia with a 15-min recovery period intervening. During the recovery period animals received an iv infusion of either isotonic glucose or mannitol. Results indicated that glucose had a beneficial effect on systolic blood pressure during the second period of asphyxia. A direct metabolic action of glucose on the myocardium is favored as the explanation, but other possibilities include peripheral or neurohumoral effects.

摘要

将麻醉后的兔子进行两次4分钟的窒息处理，中间间隔15分钟的恢复期。在恢复期，动物接受等渗葡萄糖或甘露醇的静脉输注。结果表明，葡萄糖对第二次窒息期间的收缩压有有益作用。葡萄糖对心肌的直接代谢作用被认为是一种解释，但其他可能性包括外周或神经体液作用。