Department of Otolaryngology, University of Minnesota Medical School, Children's Hospitals and Clinics of Minnesota, Minneapolis, MN 55404, USA.
JAMA Otolaryngol Head Neck Surg. 2013 Mar;139(3):231-5. doi: 10.1001/jamaoto.2013.1757.
Obstructing tracheobronchial diseases in children can be treated by a variety of techniques. The nonfiberoptic delivery of the carbon dioxide laser coupled to a rigid bronchoscope has rarely been described for this purpose and has unique advantages over other treatment methods.
To report the indications, safety, efficacy, and limitations of the carbon dioxide laser delivered through a rigid bronchoscope for tracheobronchial lesions in the pediatric population.
Case series of patients undergoing treatment for tracheobronchial lesions at a single institution from December 2, 2001, through December 14, 2011.
Tertiary care children's hospital.
Seventeen patients aged 3 months to 17 years with endotracheal and endobronchial disease.
Carbon dioxide laser treatment through a rigid bronchoscope.
Reduction in tumor burden or improvement of ventilation.
A total of 234 laser bronchoscopies were performed on 17 patients. Mean operative time was 29 (range, 2-89) minutes. Blood loss and complications were minimal. Sixteen patients received carbon dioxide laser delivered through a rigid bronchoscope with a proximal coupler or flexible fiber. The most common indication was tracheobronchial granulation tissue (n = 10), followed by prolapsed cartilage causing tracheal obstruction (n = 3), recurrent respiratory papillomatosis (n = 2), and granular cell tumor (n = 1). Of these patients, 15 (94%) underwent successful treatment. One patient was treated electively with the Nd:YAG laser owing to a vascular malformation.
The carbon dioxide laser delivered through a rigid bronchoscope is a suitable tool for managing nonvascular endotracheal and endobronchial lesions in the pediatric population. Its unique wavelength properties offer a safe, effective alternative to other lasers and open resection.
儿童阻塞性气管支气管疾病可以通过多种技术进行治疗。将二氧化碳激光通过刚性支气管镜非光纤输送用于治疗该疾病的方法很少见,与其他治疗方法相比具有独特的优势。
报告二氧化碳激光通过刚性支气管镜用于治疗儿科人群气管支气管病变的适应证、安全性、疗效和局限性。
对 2001 年 12 月 2 日至 2011 年 12 月 14 日在一家机构接受气管支气管病变治疗的患者进行的病例系列研究。
三级儿童保健医院。
17 名年龄 3 个月至 17 岁的患者,患有气管内和支气管内疾病。
通过刚性支气管镜进行二氧化碳激光治疗。
肿瘤负担减轻或通气改善。
共对 17 名患者进行了 234 次激光支气管镜检查。平均手术时间为 29 分钟(范围 2 至 89 分钟)。出血量和并发症很少。16 名患者接受了通过刚性支气管镜近端耦合器或柔性纤维输送的二氧化碳激光治疗。最常见的适应证是气管支气管肉芽组织(n=10),其次是引起气管阻塞的脱垂软骨(n=3)、复发性呼吸道乳头状瘤病(n=2)和颗粒细胞瘤(n=1)。在这些患者中,15 名(94%)患者成功接受了治疗。1 名患者因血管畸形而选择性接受 Nd:YAG 激光治疗。
二氧化碳激光通过刚性支气管镜是一种用于治疗儿科人群非血管性气管内和支气管内病变的合适工具。其独特的波长特性为其他激光和开放性切除提供了一种安全、有效的替代方法。