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开发一种脑磁图噪声生成模型,使单epoch 数据能够提取脑信号。

Development of a generative model of magnetoencephalography noise that enables brain signal extraction from single-epoch data.

机构信息

Department of Complexity Science and Engineering, The University of Tokyo, Tokyo, Japan.

出版信息

Med Biol Eng Comput. 2013 Aug;51(8):937-51. doi: 10.1007/s11517-013-1069-y. Epub 2013 May 9.

DOI:10.1007/s11517-013-1069-y
PMID:23657832
Abstract

We presented a method of rejecting sensor-specific and environmental noise during magnetoencephalography (MEG) measurement that enables the extraction of brain signals from single-epoch data. The method assumes a parametric generative model of MEG data. The model's optimal parameters were determined from single-epoch data, and noise reduction was performed by the decomposition of data within the optimal model. We confirmed our method's validity through multiple experiments. Moreover, we compared our method's performance with that of several previous noise-reduction methods. Finally, we confirmed that the proposed method followed by spatial filtering reduced noise more efficiently.

摘要

我们提出了一种在脑磁图(MEG)测量中拒绝传感器特定和环境噪声的方法,该方法可从单epoch 数据中提取脑信号。该方法假设 MEG 数据的参数生成模型。从单 epoch 数据中确定模型的最佳参数,并通过在最佳模型内分解数据来进行降噪。我们通过多个实验验证了我们方法的有效性。此外,我们还比较了我们的方法与几种先前的降噪方法的性能。最后,我们确认经过空间滤波的提出方法能够更有效地降低噪声。

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本文引用的文献

1
Removal of magnetoencephalographic artifacts with temporal signal-space separation: demonstration with single-trial auditory-evoked responses.利用时间信号空间分离去除脑磁图伪迹:单试次听觉诱发电位的验证
Hum Brain Mapp. 2009 May;30(5):1524-34. doi: 10.1002/hbm.20627.
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A robust approach to independent component analysis of signals with high-level noise measurements.
IEEE Trans Neural Netw. 2003;14(3):631-45. doi: 10.1109/TNN.2002.806648.
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Sensor noise suppression.传感器噪声抑制。
J Neurosci Methods. 2008 Feb 15;168(1):195-202. doi: 10.1016/j.jneumeth.2007.09.012. Epub 2007 Sep 19.
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Denoising based on time-shift PCA.基于时移主成分分析的去噪
J Neurosci Methods. 2007 Sep 30;165(2):297-305. doi: 10.1016/j.jneumeth.2007.06.003. Epub 2007 Jun 8.
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Spatiotemporal signal space separation method for rejecting nearby interference in MEG measurements.用于抑制脑磁图测量中附近干扰的时空信号空间分离方法。
Phys Med Biol. 2006 Apr 7;51(7):1759-68. doi: 10.1088/0031-9155/51/7/008. Epub 2006 Mar 16.
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Reduction of noise from magnetoencephalography data.减少脑磁图数据中的噪声。
Med Biol Eng Comput. 2005 Sep;43(5):630-7. doi: 10.1007/BF02351037.
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A solution to the dynamical inverse problem of EEG generation using spatiotemporal Kalman filtering.一种使用时空卡尔曼滤波解决脑电信号生成动力学逆问题的方法。
Neuroimage. 2004 Oct;23(2):435-53. doi: 10.1016/j.neuroimage.2004.02.022.
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Suppression of interference and artifacts by the Signal Space Separation Method.通过信号空间分离法抑制干扰和伪影。
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Optimization of an independent component analysis approach for artifact identification and removal in magnetoencephalographic signals.用于脑磁图信号中伪迹识别与去除的独立成分分析方法的优化
Clin Neurophysiol. 2004 May;115(5):1220-32. doi: 10.1016/j.clinph.2003.12.015.
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Speech comprehension is correlated with temporal response patterns recorded from auditory cortex.言语理解与从听觉皮层记录的时间响应模式相关。
Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13367-72. doi: 10.1073/pnas.201400998.