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来自已故供体的移植肾中因纤维肌性发育异常导致的肾动脉狭窄:彩色多普勒超声检查中的疑难诊断。

Renal artery stenosis due to fibromuscular dysplasia in a transplanted kidney from a deceased donor: a difficult diagnosis at color Doppler ultrasonography.

作者信息

Venturini M, Querques G, Margari S, Agostini G, Colombo M, Caldara R, Socci C, De Cobelli F, Del Maschio A

机构信息

Department of Radiology, San Raffaele Scientific Research Institute, Milan, Italy.

出版信息

J Clin Ultrasound. 2014 Feb;42(2):116-20. doi: 10.1002/jcu.22056. Epub 2013 May 9.

Abstract

Atherosclerotic renal artery stenosis is a frequent cause of arterial hypertension and/or allograft dysfunction after kidney transplantation and is usually located at the iliac artery anastomosis. Fibromuscular dysplasia is a less frequent, nonatherosclerotic, vascular disease, inducing stenosis at the proximal/mid-distal part of the renal artery. We report the case of a 44-year-old woman, in whom serum creatinine concentration increased and arterial hypertension developed 3 months after renal transplantation. Color Doppler ultrasonography showed a low arterial resistance index and prolonged acceleration time in the interlobar arteries, and a significantly increased peak systolic velocity at the mid third of the renal artery, demonstrating hemodynamically significant stenosis. Percutaneous transluminal angioplasty allowed stenosis correction and was followed by creatinine concentration and arterial blood pressure normalization.

摘要

动脉粥样硬化性肾动脉狭窄是肾移植后动脉高血压和/或移植肾功能障碍的常见原因,通常位于髂动脉吻合处。纤维肌性发育异常是一种较少见的非动脉粥样硬化性血管疾病,可导致肾动脉近端/中远端狭窄。我们报告了一例44岁女性患者,肾移植3个月后血清肌酐浓度升高并出现动脉高血压。彩色多普勒超声显示叶间动脉的动脉阻力指数降低、加速时间延长,肾动脉中三分之一处的收缩期峰值速度显著增加,表明存在血流动力学上有意义的狭窄。经皮腔内血管成形术纠正了狭窄,随后肌酐浓度和动脉血压恢复正常。

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