The effect of angiotensin-II during ventriculography in dogs with normal coronary arteries.

Left ventriculography was performed with and without angiotensin-II in dogs with normal coronary arteries. Concomitant administration of angiotensin significantly attenuated the myocardial depression associated with ventriculography. The beneficial effect of angiotensin may be due to its ability to maintain aortic diastolic pressure and thus flush the contrast material from the myocardium more rapidly, at least in animals without imposed coronary stenosis.