Department of Pathology and Diagnostics, University of Verona, Verona, Italy.
Clin Microbiol Infect. 2013 Sep;19(9):E409-11. doi: 10.1111/1469-0691.12232. Epub 2013 May 9.
A carbapenem-resistant Klebsiella pneumoniae was isolated from a blood-culture of an inpatient from Libya, hospitalized in the intensive-care unit of Negrar Hospital, Italy. The clinical isolate carried the following β-lactamase genes, bla(TEM -1), bla(SHV -11), bla(OXA -1), bla(CTX -M-15) and bla(OXA -48), respectively. The bla(OXA -48) gene was inserted in the Tn1999.2 transposon type, carried on a conjugative, 60-kilobase plasmid, that presented an L/M backbone, hosted by a multidrug-resistant ST 101 K. pneumoniae strain. Our report highlights the international transfer of bla(OXA -48) gene and the importance of screening measures of multidrug-resistant Enterobacteriaceae.
从利比亚一名住院患者的血培养中分离出一株耐碳青霉烯类肺炎克雷伯菌，该患者在意大利内格拉尔医院的重症监护病房住院。临床分离株携带以下β-内酰胺酶基因：bla(TEM-1)、bla(SHV-11)、bla(OXA-1)、bla(CTX-M-15)和bla(OXA-48)。bla(OXA-48)基因插入在 Tn1999.2 转座子类型中，携带在一个可接合的 60 千碱基对质粒上，该质粒具有 L/M 骨架，由一株多药耐药 ST101 K 型肺炎克雷伯菌携带。我们的报告强调了 bla(OXA-48)基因的国际转移以及对多药耐药肠杆菌科进行筛选措施的重要性。
