Kleinman P H, Miller A B, Millman R B, Woody G E, Todd T, Kemp J, Lipton D S
Narcotic & Drug Research, Inc., New York, NY 10013.
J Nerv Ment Dis. 1990 Jul;178(7):442-7. doi: 10.1097/00005053-199007000-00005.
A number of different indicators of psychopathology were assessed in this study of 76 cocaine and crack abusers who entered outpatient treatment in New York City between June and December 1987. The majority (75%) had used cocaine for 4 years or more, and the majority (62%) spent over one thousand dollars a month on cocaine in the 6 months before entry into treatment. Forty-seven percent of the sample were found to be clinically depressed. Phobic disorders were the only other axis I diagnoses found in addition to depression, and all persons who were found to have phobic disorders also were diagnosed as having some form of depressive disorder. The four most common axis II diagnoses were antisocial personality (21%), passive-aggressive (21%), borderline (18%) and self-defeating (18%). Subjects were classified as falling into one of the following three categories of a newly developed "psychopathology classification": a) no diagnosed psychopathology except substance abuse or dependency; b) one or more axis II diagnoses, but no axis I diagnoses except for substance abuse or dependency; c) at least one axis I diagnosis in addition to drug disorders whether or not accompanied by an axis II diagnosis. Mean scores on subscales and total score on the SCL-90, as well as total score on the Beck Depression Inventory, were ordered by category of the classification scheme, with those having no diagnosed psychopathology except substance abuse having the lowest score and persons in the third category having the highest score.(ABSTRACT TRUNCATED AT 250 WORDS)
在这项对76名可卡因和强效纯可卡因滥用者的研究中,评估了许多不同的精神病理学指标。这些滥用者于1987年6月至12月在纽约市接受门诊治疗。大多数人(75%)使用可卡因达4年或更长时间,并且大多数人(62%)在进入治疗前的6个月里每月在可卡因上花费超过1000美元。研究发现,47%的样本存在临床抑郁症。恐惧症是除抑郁症外唯一发现的其他轴I诊断,所有被发现患有恐惧症的人也被诊断患有某种形式的抑郁症。四个最常见的轴II诊断是反社会人格(21%)、被动攻击型(21%)、边缘型(18%)和自我挫败型(18%)。受试者被归类为新制定的“精神病理学分类”的以下三类之一:a)除物质滥用或依赖外无诊断出的精神病理学;b)有一个或多个轴II诊断,但除物质滥用或依赖外无轴I诊断;c)除药物障碍外至少有一个轴I诊断,无论是否伴有轴II诊断。根据分类方案的类别对SCL - 90分量表的平均得分、总分以及贝克抑郁量表的总分进行排序,除物质滥用外无诊断出精神病理学的人得分最低,第三类人得分最高。(摘要截选至250字)