Pusztai R, Szabó E, Béládi I
Acta Virol. 1977 Nov;21(6):449-55.
Tye specific T antigen formation has been demonstrated in primary and secondary chick embryo cells (CEC) infected with adenovirus type 12. The frequency of cells synthesizing T antigen was closely dependent on the multiplicity of infection (MOI). At a MOI of 2.85 TCD50 per cell, T antigen was formed in 50% of cells. Cycloheximide inhibited T antigen formation while cytosine arabinoside had no such effect. CEC infected with adenovirus 12 produced interferon and T antigen, both appearing early and at about the same time of infection Exogenous chick interferon had no inhibitory effect on the formation of T antigen. In adenovirus 12-infected CEC, virus specific structural antigen could not be detected.
在感染12型腺病毒的原代和传代鸡胚细胞（CEC）中已证实了特异性T抗原的形成。合成T抗原的细胞频率紧密依赖于感染复数（MOI）。在每细胞2.85个TCD50的MOI下，50%的细胞形成了T抗原。环己酰亚胺抑制T抗原的形成，而阿糖胞苷则没有这种作用。感染12型腺病毒的CEC产生干扰素和T抗原，两者均在感染早期且大约在同一时间出现。外源性鸡干扰素对T抗原的形成没有抑制作用。在感染12型腺病毒的CEC中，无法检测到病毒特异性结构抗原。
