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原发性睾丸浆细胞瘤:五年随访

Primary testicular plasmocytoma: A five year follow-up.

作者信息

Filho Milton Ghirelli

机构信息

Grajaú Hospital Urological Clinic, Grajaú Hospital, Rua Francisco Otávio Pacca, 180, Grajaú, São Paulo, SP, Brazil.

出版信息

Urol Ann. 2013 Jan;5(1):39-41. doi: 10.4103/0974-7796.106965.

Abstract

The testicular plasmocytoma represents only 5% of the non-germinative cell testicular tumors, and accounts for only 2% of all plasma cell neoplasms. Approximately, 50 cases of testicular plasmocytoma have been reported in medical literature; however, only 9 of these are isolated tumors without previous history or progression to multiple myeloma. A 47-year-old patient, presenting progressive and painless growth of the right testicle in the last four years, underwent surgical treatment in another hospital two years ago, to correct a hydrocele in the same testicle with no improvement at all. Sonography showed a tumor with the following measurements for the right testicle: 84 × 59 × 80 mm. The tumor marker values were all normal. An abdominal computed tomography found no evidence of retroperitoneal lymph nodes invasion. The patient underwent a right radical orchiectomy. Pathologic analysis revealed a malignant neoplasia described as a plasmocytoma (solitary myeloma) that produces immunoglobulin's kappa light chain. After five years of follow-up, there were no signs of metastasis or local recurrence in the exams. Case report and review of literature have been presented here.

摘要

睾丸浆细胞瘤仅占非生殖细胞性睾丸肿瘤的5%,在所有浆细胞肿瘤中仅占2%。医学文献中大约报道了50例睾丸浆细胞瘤;然而,其中只有9例是孤立性肿瘤,没有既往病史或进展为多发性骨髓瘤。一名47岁患者,在过去四年中右侧睾丸出现进行性无痛性增大,两年前在另一家医院接受了手术治疗,以纠正同一睾丸的鞘膜积液,但毫无改善。超声检查显示右侧睾丸肿瘤大小为84×59×80mm。肿瘤标志物值均正常。腹部计算机断层扫描未发现腹膜后淋巴结侵犯的证据。该患者接受了右侧根治性睾丸切除术。病理分析显示为一种恶性肿瘤,描述为产生免疫球蛋白κ轻链的浆细胞瘤(孤立性骨髓瘤)。经过五年的随访,检查中未发现转移或局部复发的迹象。本文呈现了病例报告及文献回顾。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e24/3643322/2a3c88c2ffad/UA-5-39-g001.jpg

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引用本文的文献

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An extramedullary plasmacytoma in the testicle: A case report and review of the literature.
Can Urol Assoc J. 2015 Mar-Apr;9(3-4):E240-2. doi: 10.5489/cuaj.2531.

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