von Ardenne M
Wien Klin Wochenschr. 1975 Jan 10;87(1):7-12.
The noticeable improvement in the supply of glucose and oxygen to surviving cancer cells located far from the capillary region (primarily very slowly proliferating or non-proliferating cancer cells) can be taken as the main reason for cancer recurrence in the wake of successful tumour treatment with destruction of a high percentage of cancer cells. On the basis of theoretical and experimental research work on substrate supply, cell kinetics and therapy mechanisms in the intercapillary region, therapeutic steps are formulated which act on cancer cells situated at a greater distance from the capillaries and, therefore, against the genesis of cancer recurrence as such.
在成功治疗肿瘤并破坏了高比例癌细胞后，向远离毛细血管区域的存活癌细胞（主要是增殖非常缓慢或不增殖的癌细胞）供应葡萄糖和氧气的显著改善，可被视为癌症复发的主要原因。基于对毛细血管间区域底物供应、细胞动力学和治疗机制的理论和实验研究工作，制定了针对位于离毛细血管较远位置的癌细胞的治疗步骤，从而对抗癌症复发的发生。
