[孕期碘摄入：对母婴甲状腺功能的影响]
[Iodine intake during pregnancy: effects on thyroid function in mother and child].
作者信息
Suárez Rodríguez Marta, Azcona San Julián Cristina, Alzina de Aguilar Valentín
机构信息
Área de Gestión Clínica de Pediatría, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
出版信息
Endocrinol Nutr. 2013 Aug-Sep;60(7):352-7. doi: 10.1016/j.endonu.2013.01.010. Epub 2013 May 8.
INTRODUCTION
Recent studies in Spain have shown an inadequate iodine intake in a significant proportion of pregnant women. Pregnancy increases thyroid hormone requirements, and adequate iodine intake is therefore needed.
MATERIAL AND METHODS
One hundred and forty-seven women in their third trimester (week 37) of pregnancy provided a blood sample and a 24-hour urine sample to test serum and urine iodine levels and completed a food frequency questionnaire to assess iodine intake during pregnancy. Serum TSH levels were measured in the babies born to the 140 mothers in the postpartum group.
RESULTS
Only 10.9% of pregnant women consumed more than 250 μg iodine daily, and 24.4% of them consumed less than 100 μg daily. Mean free T4 levels were 9.37 pmol/L, and 74 women (54.41%) had levels below the hypothyroxinemia threshold. TSH levels were normal in 135 newborns (96.4%), while 5 (3.6%) had levels higher than 5 μU/mL.
引言
西班牙最近的研究表明，相当一部分孕妇碘摄入量不足。怀孕会增加甲状腺激素需求，因此需要充足的碘摄入。
材料与方法
147名处于妊娠晚期（第37周）的孕妇提供了一份血样和一份24小时尿样，以检测血清和尿碘水平，并完成了一份食物频率问卷，以评估孕期的碘摄入量。对产后组中140名母亲所生婴儿的血清促甲状腺激素（TSH）水平进行了测量。
结果
只有10.9%的孕妇每天摄入超过250微克碘，24.4%的孕妇每天摄入少于100微克碘。游离甲状腺素（T4）平均水平为9.37皮摩尔/升，74名女性（54.41%）的水平低于低甲状腺素血症阈值。135名新生儿（96.4%）的TSH水平正常，5名（3.6%）的TSH水平高于5微单位/毫升。
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