Centre for Population Health, Burnet Institute, Melbourne, Victoria 3004, Australia; Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria 3004, Australia.
Drug Alcohol Depend. 2013 Oct 1;132(3):541-6. doi: 10.1016/j.drugalcdep.2013.03.021. Epub 2013 May 9.
Limited evidence suggests that younger people who inject drugs (PWID) engage in high-risk injecting behaviours. This study aims to better understand the relationships between age and risky injecting behaviours.
Data were taken from 11 years of a repeat cross-sectional study of sentinel samples of regular PWID (The Australian Illicit Drug Reporting System, 2001-2011). Multivariable Poisson regression was used to explore the relationship between age and four outcomes of interest: last drug injection occurred in public, receptive needle sharing (past month), experiencing injecting-related problems (e.g. abscess, dirty hit; past month), and non-fatal heroin overdose (past six months).
Data from 6795 first-time study participants were analysed (median age: 33 years, interquartile range [IQR]: 27-40; median duration of injecting: 13 years [IQR: 7-20]). After adjusting for factors including duration of injecting, each five year increase in age was associated with significant reductions in public injecting (adjusted incidence rate ratio [AIRR]: 0.90, 95% confidence interval [CI]: 0.88-0.92), needle sharing (AIRR: 0.84, 95% CI: 0.79-0.89) and injecting-related problems (AIRR: 0.96, 95% CI: 0.95-0.97). Among those who had injected heroin in the six months preceding interview, each five year increase in age was associated with an average 10% reduction in the risk of heroin overdose (AIRR: 0.90, 95% CI: 0.85-0.96).
Older PWID report significantly lower levels of high-risk injecting practices than younger PWID. Although they make up a small proportion of the current PWID population, younger PWID remain an important group for prevention and harm reduction.
有限的证据表明,年轻的吸毒者(PWID)会从事高风险的注射行为。本研究旨在更好地了解年龄与高风险注射行为之间的关系。
数据来自于一项对常规吸毒者(澳大利亚非法药物报告系统,2001-2011 年)的哨点样本进行的重复横断面研究的 11 年数据。多变量泊松回归用于探索年龄与四个感兴趣结果之间的关系:最后一次药物注射发生在公共场所、接受性针具共享(过去一个月)、经历与注射相关的问题(例如脓肿、脏针;过去一个月)以及非致命性海洛因过量(过去六个月)。
分析了来自 6795 名首次研究参与者的数据(中位数年龄:33 岁,四分位距[IQR]:27-40;中位数注射持续时间:13 年[IQR:7-20])。在调整了包括注射持续时间在内的各种因素后,年龄每增加五年,与在公共场所注射的显著减少相关(调整后的发病率比[AIRR]:0.90,95%置信区间[CI]:0.88-0.92)、针具共享(AIRR:0.84,95% CI:0.79-0.89)和与注射相关的问题(AIRR:0.96,95% CI:0.95-0.97)。在接受访谈前六个月内注射过海洛因的人群中,年龄每增加五年,海洛因过量的风险平均降低 10%(AIRR:0.90,95% CI:0.85-0.96)。
年长的吸毒者报告的高风险注射行为明显低于年轻的吸毒者。尽管他们在当前吸毒者群体中占很小的比例,但年轻的吸毒者仍然是预防和减少伤害的一个重要群体。