Institute of Neuroscience and Physiology, Epilepsy Research Group, University of Gothenburg, Sweden.
Epilepsy Behav. 2013 Jul;28(1):127-31. doi: 10.1016/j.yebeh.2013.03.001. Epub 2013 May 11.
Knowledge about long-term psychosocial outcome of temporal lobe resection (TLR) for epilepsy is limited. The aims of this study were to describe vocational outcome 10 years after TLR and to analyze the effect on the vocational situation by seizures, laterality of resection, verbal memory, and mood. Fifty-one patients were prospectively followed 10 years after TLR. Psychosocial and neuropsychological data were ascertained at baseline and 10 years after surgery and at corresponding time points for 23 controls. Fewer patients worked 10 years post-operatively compared with controls (TLR patients: 61% and controls: 96%). However, seizure-free patients were more likely to retain employment (71%) than patients who had seizures (41%). The odds of working full-time were 9.5 times higher for patients with seizure freedom than for those with continuing seizures. There were no associations between working at 10 years and side of resection or mood, and impairment of verbal memory did not have an influence on vocational outcome.
关于颞叶切除术（TLR）治疗癫痫的长期心理社会结局的知识有限。本研究的目的是描述 TLR 后 10 年的职业结果，并分析癫痫发作、切除侧、言语记忆和情绪对职业状况的影响。51 例患者前瞻性随访 TLR 后 10 年。在手术前和手术后 10 年以及相应的时间点，对心理社会和神经心理学数据进行了评估，并与 23 名对照进行了比较。与对照组相比（TLR 患者：61%，对照组：96%），术后 10 年患者的工作人数较少。然而，无癫痫发作的患者更有可能保留工作（71%），而有癫痫发作的患者（41%）则较少。与持续癫痫发作的患者相比，无癫痫发作的患者全职工作的可能性高 9.5 倍。在 10 年内工作与切除侧或情绪之间没有关联，言语记忆的损害对职业结果没有影响。
