Department of Dermatology, Postgraduate Institute of Medical Education, Chandigarh, India.
J Cutan Med Surg. 2013 May-Jun;17(3):180-8. doi: 10.2310/7750.2012.12048.
The mucocutaneous lesions in Reiter syndrome (RS) or reactive arthritis are seen quite frequently.
The case records of patients admitted with the diagnosis of RS from January 2006 to December 2010 were reviewed. Data regarding the demographic details; course of musculoskeletal, mucocutaneous, and ophthalmic involvement; body surface area affected; morphology of lesions; investigations undertaken; and treatment instituted were recorded. Based on these, the disease was classified as complete or incomplete RS.
The case records of 11 patients were evaluated. There were seven males and four females. Only two patients had complete RS, whereas nine patients had incomplete RS. Arthritis and mucocutaneous involvement were seen in all 11 patients, whereas preceding urethritis/dysentery was seen in 4 patients and eye symptoms in 4 patients. Enthesitis was seen in eight patients (72.7%). Circinate balanitis/vulvitis was present in six patients and keratoderma blenorrhagicum in eight patients. The most frequent radiologic finding was juxta-articular osteopenia in eight patients.
RS may not show the typical triad in all cases, although musculoskeletal disease is seen in a significant proportion of patients. In the absence of typical signs and symptoms, cutaneous manifestations may help establish the diagnosis of RS.
反应性关节炎(Reiter 综合征,RS)或反应性关节炎患者常出现黏膜皮肤损伤。
对 2006 年 1 月至 2010 年 12 月期间以 RS 诊断入院的患者的病历记录进行了回顾。记录了人口统计学细节、肌肉骨骼、黏膜皮肤和眼部受累的病程、受累体表面积、病变形态、所进行的检查和所实施的治疗等数据。在此基础上,将疾病分为完全性和不完全性 RS。
评估了 11 例患者的病历记录。其中男 7 例,女 4 例。仅有 2 例患者为完全性 RS,9 例为不完全性 RS。11 例患者均出现关节炎和黏膜皮肤受累,4 例患者出现尿道炎/痢疾前症,4 例患者出现眼部症状。8 例患者存在附着点炎(72.7%)。6 例患者存在环状外阴炎/阴道炎,8 例患者存在增殖性脓皮病。8 例患者最常见的放射学发现是关节旁骨质疏松。
虽然在很大一部分患者中存在肌肉骨骼疾病,但 RS 并非在所有病例中均出现典型三联征。在没有典型体征和症状的情况下,皮肤表现可能有助于确立 RS 的诊断。