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糖尿病性和特发性神经病变叠加的下肢周围神经卡压症的外科治疗

Surgical treatment of superimposed, lower extremity, peripheral nerve entrapments with diabetic and idiopathic neuropathy.

作者信息

Valdivia Valdivia Juan Martin, Weinand Martin, Maloney Christopher T, Blount Andrew L, Dellon Arnold Lee

机构信息

Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA.

出版信息

Ann Plast Surg. 2013 Jun;70(6):675-9. doi: 10.1097/SAP.0b013e3182764fb0.

DOI:10.1097/SAP.0b013e3182764fb0
PMID:23673565
Abstract

BACKGROUND

Although it is recognized that people with peripheral neuropathy have an increased prevalence of chronic nerve entrapment, controversy still exists over their management. The present report details the evaluation, surgical approach, and outcome of a large cohort of people with diabetic and with idiopathic neuropathy.

METHODS

A retrospective review of 158 consecutive patients, 96 with diabetic and 62 with idiopathic neuropathy, was done to analyze the results of neurolysis of multiple sites of chronic nerve compression in the lower extremity. Of these patients, 50 had a contralateral limb decompressed for a total of 208 limbs included in the study. Outcomes included visual analog scale (VAS) for pain in the 109 patients who had pain level greater than 8.0, measurement of the cutaneous pressure threshold for sensibility, self-reported change in pain medication usage, and self-reported change in balance.

RESULTS

With a minimum follow-up of 1 year, 88% of patients with preoperative numbness reported improvement in sensation (P < 0.001). Of the 84 patients with impaired balance, 81% reported improvement in balance. Of those whose VAS was greater than 8, 83% reported an improvement in VAS (P < 0.001). There was a concomitant reduction in pain medication usage. There was no difference in outcomes between patients with diabetic versus idiopathic neuropathy in response to nerve decompression.

CONCLUSIONS

Neurolysis of lower extremity chronic nerve compressions in patients with neuropathy and superimposed nerve compressions is an effective method for relieving pain, restoring sensation, and improving balance.

摘要

背景

尽管人们认识到周围神经病变患者慢性神经卡压的患病率增加,但在其治疗方面仍存在争议。本报告详细介绍了一大群糖尿病性和特发性神经病变患者的评估、手术方法及结果。

方法

对158例连续患者进行回顾性研究,其中96例为糖尿病性神经病变患者,62例为特发性神经病变患者,分析下肢多处慢性神经受压松解术的结果。这些患者中,50例对侧肢体也进行了减压,研究共纳入208条肢体。结果包括对109例疼痛程度大于8.0的患者采用视觉模拟评分法(VAS)评估疼痛、测量皮肤感觉压力阈值、患者自我报告的止痛药物使用变化以及自我报告的平衡变化。

结果

随访至少1年,术前有麻木感的患者中,88%报告感觉改善(P < 0.001)。84例平衡功能受损的患者中,81%报告平衡功能改善。VAS大于8的患者中,83%报告VAS改善(P < 0.001)。止痛药物使用也随之减少。糖尿病性神经病变患者与特发性神经病变患者在神经减压后的结果无差异。

结论

对合并神经卡压的神经病变患者进行下肢慢性神经受压松解术是缓解疼痛、恢复感觉和改善平衡的有效方法。

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