Radenbach D, Morgenroth K, Staud R D, Magnussen H
Krankenhaus Grosshansdorf, Zentrum für Pneumologie und Thoraxchirurgie, LVA Hamburg.
Pneumologie. 1990 Feb;44 Suppl 1:250-1.
We observed two patients who, after inhaling glass fibre dust for 14 and 16 years, respectively, developed a cough and dyspnoea on exertion. Our investigation of transbronchially obtained lung tissue with the aid of light microscopy, electron microscopy and energy-dispersive x-ray micro-analysis revealed fibrosis of mild extension in immediate topographical relationship to phagocytosed fragments of glass fibre. We conclude from these findings that inhaled glass fibre dust can develop a fibrogenic effect.
我们观察了两名患者，他们分别在吸入玻璃纤维粉尘14年和16年后，出现了咳嗽和劳力性呼吸困难。我们借助光学显微镜、电子显微镜和能量色散X射线微分析对经支气管获取的肺组织进行研究，结果显示，在与吞噬的玻璃纤维碎片紧邻的局部区域有轻度的纤维化。从这些发现中我们得出结论，吸入玻璃纤维粉尘可产生致纤维化效应。
