Loos U, Musch E, Schwabe H K
Medizinische Universitätsklinik Bonn.
Pneumologie. 1990 Feb;44 Suppl 1:488-9.
In a pilot study involving 62 patients with open pulmonary tuberculosis, we established that slow acetyators and patients receiving intravenous rifampicin treatment showed a tendency towards a more rapid negativisation of the sputum culture than did fast acetyators (lower levels of isoniazid) or patients receiving oral rifampicin therapy (decreasing bioavailability of the rifampicin during treatment).
在一项针对62例开放性肺结核患者的初步研究中，我们发现，慢乙酰化者以及接受静脉注射利福平治疗的患者，与快乙酰化者（异烟肼水平较低）或接受口服利福平治疗的患者（治疗期间利福平的生物利用度降低）相比，痰培养转阴的速度有更快的趋势。
