Isaka Mitsuhiro, Asai Katsuyuki, Urabe Norikazu
Division of Thoracic Surgery, Numazu City Hospital, Numazu, Shizuoka, Japan.
Interact Cardiovasc Thorac Surg. 2013 Aug;17(2):247-52. doi: 10.1093/icvts/ivt221. Epub 2013 May 14.
Secondary spontaneous pneumothorax (SSP) is more common in elderly patients; it has high rates of recurrence and mortality, even if surgery is performed. There has been little study on the surgical treatment of SSP. Therefore, we analysed the outcomes of surgical treatment of SSP patients, and investigated the risk factors of recurrence and morbidity.
We studied 97 consecutive surgical treatments on 94 patients with SSP who had emphysematous changes of lung retrospectively. Emphysematous changes on preoperative computed tomography image were evaluated by the Goddard score, which is a visual scoring system. First, video-assisted thoracoscopic surgery was performed, followed by bullectomy for the responsible lesions.
The rate of morbidity was 20.6% and that of mortality was 4.1%. Recurrence rate was 9.3%. By multivariate analysis, a Goddard score≥7 (odds ratio: 8.93, P=0.033) and treatment of bulla without the use of staplers (odds ratio: 11.57, P=0.019) were significant risk factors for morbidity, while pulmonary fibrosis tended to increase the risk of recurrence (hazard ratio: 4.21, P=0.051), and a Goddard score≥7 (hazard ratio: 7.79, P=0.023) was a significant risk factor for recurrence.
Surgical treatment in patients with SSP had favourable results. Treatment in which the base of the bulla cannot be definitely shut off with staplers is associated with increased morbidity. Significant emphysematous change on preoperative computed tomography image and pulmonary fibrosis are predictors of recurrence. Patients with these findings should be investigated in terms of the indications of surgery and additional treatment, not only bullectomy.
继发性自发性气胸(SSP)在老年患者中更为常见;即使进行手术,其复发率和死亡率也很高。关于SSP的外科治疗研究较少。因此,我们分析了SSP患者外科治疗的结果,并调查了复发和发病的危险因素。
我们回顾性研究了94例患有肺气肿样肺改变的SSP患者的97例连续外科治疗。术前计算机断层扫描图像上的肺气肿样改变通过戈达德评分进行评估,这是一种视觉评分系统。首先,进行电视辅助胸腔镜手术,然后对相关病变进行肺大疱切除术。
发病率为20.6%,死亡率为4.1%。复发率为9.3%。通过多变量分析,戈达德评分≥7(比值比:8.93,P = 0.033)和不使用吻合器治疗肺大疱(比值比:11.57,P = 0.019)是发病的显著危险因素,而肺纤维化倾向于增加复发风险(风险比:4.21,P = 0.051),戈达德评分≥7(风险比:7.79,P = 0.023)是复发的显著危险因素。
SSP患者的外科治疗取得了良好的效果。无法用吻合器确切关闭肺大疱底部的治疗与发病率增加有关。术前计算机断层扫描图像上显著的肺气肿样改变和肺纤维化是复发的预测因素。对于有这些发现的患者,不仅应考虑肺大疱切除术,还应从手术指征和额外治疗方面进行评估。