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胸腔镜辅助下肺大疱切除术和胸膜部分切除术与胸腔引流管治疗继发性自发性气胸的疗效比较:一项回顾性单中心分析。

Video-Assisted Thoracoscopic Surgery with Bullectomy and Partial Pleurectomy versus Chest Tube Drainage for Treatment of Secondary Spontaneous Pneumothorax-A Retrospective Single-Center Analysis.

机构信息

Department of Surgery, University Hospital Duesseldorf and Heinrich-Heine-University Duesseldorf, 40225 Duesseldorf, Germany.

出版信息

Medicina (Kaunas). 2022 Feb 27;58(3):354. doi: 10.3390/medicina58030354.

Abstract

Background and objective: Current guidelines recommend chest tube (CT) drainage as the initial treatment of secondary spontaneous pneumothorax (SSP). Surgery should be considered in cases of persistent air leak or recurrent disease. Video-assisted thoracoscopic surgery (VATS) is nowadays an established surgical treatment for complicated spontaneous pneumothorax. However, reports on VATS-bullectomy with partial pleurectomy (VBPP) for treatment of secondary spontaneous pneumothorax (SSP) are limited. The primary aim of this study was to evaluate and compare the clinical outcomes of patients with secondary pneumothorax treated either by VBPP or CT drainage in our institution. Secondly, we assessed underlying clinical parameters to identify potential risk factors for SSP recurrence. Materials and Methods: Eighty-two patients were included in this study. Long-term recurrence rates and potential risk factors for SSP recurrence were analyzed. Results: Thirty-six patients (43.9%) underwent VBPP, whereas 46 (56.1%) patients subsequently underwent CT treatment. During a median follow-up period of 76.5 months, VBPP patients experienced a significantly low recurrence rate compared to CT patients (VBPP vs. CT: 16.7% vs. 41.3%; p = 0.016). However, VBPP was associated with a higher complication rate and significantly longer length of hospital stay (LOS). Male sex (male vs. female: p = 0.021) and CT treatment (VBPP vs. CT: p < 0.001) were identified as potential risk factors for SSP recurrence. Conclusions: VBPP is a suitable surgical treatment for SSP. However, prolonged LOS and possible complications should be discussed prior to VBPP.

摘要

背景和目的

目前的指南建议胸腔引流管(CT)引流作为继发性自发性气胸(SSP)的初始治疗方法。对于持续性漏气或复发性疾病,应考虑手术。如今,电视辅助胸腔镜手术(VATS)已成为治疗复杂性自发性气胸的一种既定手术治疗方法。然而,关于 VATS 肺大疱切除术联合部分胸膜切除术(VBPP)治疗继发性自发性气胸(SSP)的报道有限。本研究的主要目的是评估和比较我院采用 VBPP 或 CT 引流治疗继发性气胸患者的临床结果。其次,我们评估了潜在的临床参数,以确定 SSP 复发的潜在危险因素。

材料和方法

本研究共纳入 82 例患者。分析了长期复发率和 SSP 复发的潜在危险因素。

结果

36 例(43.9%)患者接受 VBPP 治疗,46 例(56.1%)患者随后接受 CT 治疗。在 76.5 个月的中位随访期间,VBPP 患者的复发率明显低于 CT 患者(VBPP 与 CT:16.7%与 41.3%;p=0.016)。然而,VBPP 与更高的并发症发生率和显著更长的住院时间(LOS)相关。男性(男性与女性:p=0.021)和 CT 治疗(VBPP 与 CT:p<0.001)被确定为 SSP 复发的潜在危险因素。

结论

VBPP 是治疗 SSP 的一种合适的手术治疗方法。然而,在进行 VBPP 之前,应讨论延长 LOS 和可能的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be4f/8955106/8c2f7176444e/medicina-58-00354-g001.jpg

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