Treiber F A, Musante L, Braden D, Arensman F, Strong W B, Levy M, Leverett S
Department of Pediatrics, Medical College of Georgia, Augusta 30912-3770.
Psychosom Med. 1990 May-Jun;52(3):286-96. doi: 10.1097/00006842-199005000-00003.
The prevalence of essential hypertension is higher among blacks than whites. One reason for this difference may be that blacks are more reactive to stressors that produce vasoconstrictive responses. Two studies were conducted to test this hypothesis, one with 10- to 14-year-old males (20 whites, 20 blacks) and one with young adult males (10 whites, 10 blacks). Subjects had blood pressure, heart rate, cardiac output, and total peripheral resistance measured before, during, and after exposure to forehead cold stimulation. In both studies, blacks exhibited greater increases in diastolic blood pressure and total peripheral resistance to the stressor than whites. The findings are discussed in relation to blacks' greater pressor reactivity to stress, which appears to be mediated by changes in total peripheral resistance.
原发性高血压的患病率在黑人中高于白人。造成这种差异的一个原因可能是,黑人对产生血管收缩反应的应激源反应更强。进行了两项研究来验证这一假设,一项研究的对象是10至14岁的男性(20名白人、20名黑人),另一项研究的对象是年轻成年男性(10名白人、10名黑人)。在接触前额冷刺激之前、期间和之后,测量受试者的血压、心率、心输出量和总外周阻力。在两项研究中,黑人的舒张压和总外周阻力相对于应激源的升高幅度均大于白人。结合黑人对应激的升压反应更强这一现象对研究结果进行了讨论,这种升压反应似乎是由总外周阻力的变化介导的。