文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Biochim Biophys Acta. 1975 Mar 28;384(1):138-45. doi: 10.1016/0005-2744(75)90103-5.

Cholesterol ester hydrolytic activity (sterol-ester hydrolase EC 3.1.1.13) was detected in human red blood cells. Enzyme activity appeared confined to the cell membrane and was most marked in washed preparations of red cell ghosts. 2. Hydrolytic activity was stimulated by the anti-oxidants D-alpha-tocopherol and butylated hydroxytoluene. Marked inhibition was produced by erythrocyte hemolysate, sodium taurocholate, and Triton X-100. 3. Optimal pH for the reaction was 5.4--5.7. 4. Because red cell cholesterol is all unesterified, it is speculated that the hydrolase serves to maintain the erythrocyte membrane free of esterified cholesterol.

在人红细胞中检测到胆固醇酯水解活性（甾醇酯水解酶，EC 3.1.1.13）。酶活性似乎局限于细胞膜，在洗涤过的红细胞影制备物中最为明显。2. 抗氧化剂D-α-生育酚和丁基羟基甲苯可刺激水解活性。红细胞溶血产物、牛磺胆酸钠和 Triton X-100可产生明显抑制作用。3. 该反应的最适pH为5.4 - 5.7。4. 由于红细胞胆固醇全部未酯化，推测该水解酶有助于维持红细胞膜不含酯化胆固醇。

Biochim Biophys Acta. 1975 Mar 28;384(1):138-45. doi: 10.1016/0005-2744(75)90103-5.

Cholesterol ester hydrolytic activity (sterol-ester hydrolase EC 3.1.1.13) was detected in human red blood cells. Enzyme activity appeared confined to the cell membrane and was most marked in washed preparations of red cell ghosts. 2. Hydrolytic activity was stimulated by the anti-oxidants D-alpha-tocopherol and butylated hydroxytoluene. Marked inhibition was produced by erythrocyte hemolysate, sodium taurocholate, and Triton X-100. 3. Optimal pH for the reaction was 5.4--5.7. 4. Because red cell cholesterol is all unesterified, it is speculated that the hydrolase serves to maintain the erythrocyte membrane free of esterified cholesterol.

在人红细胞中检测到胆固醇酯水解活性（甾醇酯水解酶，EC 3.1.1.13）。酶活性似乎局限于细胞膜，在洗涤过的红细胞影制备物中最为明显。2. 抗氧化剂D-α-生育酚和丁基羟基甲苯可刺激水解活性。红细胞溶血产物、牛磺胆酸钠和 Triton X-100可产生明显抑制作用。3. 该反应的最适pH为5.4 - 5.7。4. 由于红细胞胆固醇全部未酯化，推测该水解酶有助于维持红细胞膜不含酯化胆固醇。