König H, Sieper J, Wolf K J
Department of Radiology, Klinikum Steglitz, Free University of Berlin, Federal Republic of Germany.
Radiology. 1990 Aug;176(2):473-7. doi: 10.1148/radiology.176.2.2367663.
The knees of 20 patients with rheumatoid arthritis and two healthy volunteers were evaluated with magnetic resonance (MR) imaging. Spin-echo sequences were performed, and the signal-intensity patterns of normal and pathologic articular soft-tissue structures were quantitatively evaluated with a dynamic FLASH (fast low-angle shot) sequence after bolus intravenous injection of gadolinium diethylenetriaminepentaacetic acid. In contrast to the spin-echo images obtained before injection of contrast material, it appears possible with this technique to distinguish joint effusion from hypervascular pannus formations and to grade the vascularity of proliferative synovitis. Flat pannus deposits on the articular surface and subchondral pannus masses were identified only by their marked enhancement of signal intensity after injection of contrast material. Dynamic MR imaging appears to yield decisive information for diagnosing rheumatoid arthritis.
对20例类风湿性关节炎患者的膝关节以及两名健康志愿者的膝关节进行了磁共振（MR）成像评估。采用自旋回波序列，并在静脉推注钆二乙三胺五乙酸后，用动态FLASH（快速低角度激发）序列对正常和病理性关节软组织结构的信号强度模式进行定量评估。与注射造影剂前获得的自旋回波图像相比，使用该技术似乎可以区分关节积液与血管丰富的血管翳形成，并对增生性滑膜炎的血管情况进行分级。仅通过注射造影剂后信号强度的明显增强，才能识别出关节表面的扁平血管翳沉积物和软骨下血管翳肿块。动态MR成像似乎可为诊断类风湿性关节炎提供决定性信息。
