König H, Sieper J, Wolf K J
Abteilung für Röngendiagnostik, Klinikum Steglitz der Freien Universität Berlin.
Rofo. 1990 Jul;153(1):1-5. doi: 10.1055/s-2008-1033323.
Eighteen patients with inflammatory lesions of the knee joints (ten with rheumatoid arthritis, eight with undiagnosed lesions) and two normal subjects were examined by MRI. In addition to spin-echo measurements, the signals from normal and pathological tissues were evaluated quantitatively by dynamic flash sequences following the injection of gadolinium DTPA. The latter method was able to distinguish active pannus from other proliferative synovial changes; the degree of activity could be related to synovial histology and relevant clinical features in eight patients. Areas of flat articular and subchondral pannus could be identified by the enhanced signal following the administration of gadolinium DTPA. Dynamic MRI is able to provide important information for the early diagnosis and follow-up of patients with rheumatoid arthritis.
18例膝关节炎性病变患者（10例类风湿性关节炎患者，8例病变未确诊患者）和2名正常受试者接受了磁共振成像（MRI）检查。除了自旋回波测量外，在注射钆喷替酸葡甲胺后，通过动态快速成像序列对正常和病理组织的信号进行了定量评估。后一种方法能够区分活性血管翳与其他增殖性滑膜改变；8例患者的活性程度与滑膜组织学及相关临床特征有关。注射钆喷替酸葡甲胺后信号增强可识别扁平关节和软骨下血管翳区域。动态MRI能够为类风湿性关节炎患者的早期诊断和随访提供重要信息。
