Department of Neurology, University of Michigan Health System, Ann Arbor, MI 48109-5036, USA.
Semin Neurol. 2012 Nov;32(5):500-5. doi: 10.1055/s-0033-1334468. Epub 2013 May 15.
Multifocal motor neuropathy is an acquired disorder in which demyelination of motor axons, presumably due to autoimmune attack, results in progressive painless weakness without sensory loss. Motor axonal damage also occurs. It is a frequent mimic of motor neuron disease. Recognition of multifocal motor neuropathy is critical because it tends to be very responsive to treatment. Infusion of intravenous immunoglobulin is the initial treatment of choice, but other immunosuppressive treatments may also be effective. It appears that corticosteroids produce minimal benefit.
多灶性运动神经病是一种获得性疾病，其运动轴突脱髓鞘，推测是由于自身免疫攻击所致，导致进行性无痛性无力而无感觉丧失。运动轴突损伤也会发生。它是运动神经元病的常见模拟疾病。识别多灶性运动神经病非常重要，因为它往往对治疗反应良好。静脉注射免疫球蛋白是首选的初始治疗方法，但其他免疫抑制治疗也可能有效。皮质类固醇似乎益处极小。
