Sirenko Iu N, Savitskiĭ S Iu, Krasnitskiĭ S S, Shabil'ianov A V, Popova L I
Sov Med. 1990(3):18-21.
A total of 119 patients with myocardial infarction hospitalized within 24 hrs from the disease onset were examined. He-Ne laser irradiation of the blood (daily 40 min sessions for 3-5 days) was carried out in 45 patients (Group 1). The rest 74 patients (Group 2) were administered common therapy. A number of biologically active substances were radioimmunoassayed in the blood of 12 Group 1 and 11 Group 2 patients on days 1, 3, and 7 of the disease. The pain syndrome was alleviated in Group 1 patients, in contrast to Group 2 patients, and the frequencies of ventricular arrhythmias, of heart failures, and of the condition recurrences were reduced, as was the mortality rate. Laser therapy resulted in reduction of the activities of the hypophyseoadrenocortical and aldosteron-renin-angiotensin systems. Besides blood levels of dilatants and proaggregants (PGF2 alpha, vasopressin, angiotensin II) reduced in these patients, whereas vasodilating and antiaggregation hormones (PGE, PGI2) levels increased and the PGI2/TxB2 ratio improved.
对119例发病后24小时内住院的心肌梗死患者进行了检查。45例患者（第1组）接受了血液氦氖激光照射（每天照射40分钟，持续3 - 5天）。其余74例患者（第2组）接受常规治疗。在发病第1天、第3天和第7天，对第1组的12例患者和第2组的11例患者的血液中的多种生物活性物质进行了放射免疫分析。与第2组患者相比，第1组患者的疼痛综合征得到缓解，室性心律失常、心力衰竭和病情复发的频率降低，死亡率也降低。激光治疗导致垂体肾上腺皮质系统和醛固酮 - 肾素 - 血管紧张素系统的活性降低。此外，这些患者血液中舒张剂和促聚集剂（前列腺素F2α、血管加压素、血管紧张素II）的水平降低，而血管舒张和抗聚集激素（前列腺素E、前列环素I2）的水平升高，且前列环素I2/血栓素B2比值改善。
