Gilks W R, Gore S M, Bradley B A
Biostatistics Unit, Medical Research Council, Cambridge, England.
Transplantation. 1990 Jul;50(1):141-6.
Many studies have shown long-term benefits of HLA matching in kidney transplantation. By examining rates of graft loss within consecutive posttransplant intervals, using data from the UK Transplant Service, we show that the long-term benefits of HLA matching are due to reduction of the graft failure rate within five months of transplantation. After 5-months, HLA-A,B,DR matching appears to have little impact on graft loss. We suggest that graft losses after 5 months may be attributable to non-HLA targets.
许多研究表明，HLA配型在肾移植中具有长期益处。通过利用英国移植服务机构的数据，检查连续移植后各时间段内的移植物丢失率，我们发现HLA配型的长期益处源于移植后五个月内移植失败率的降低。五个月后，HLA - A、B、DR配型似乎对移植物丢失影响不大。我们认为，五个月后的移植物丢失可能归因于非HLA靶点。
