Patel J, Worthen R, Abadir R, Weaver D J, Weinstein S, Ross G
Division of Urology, University of Missouri School of Medicine, Columbia.
Urology. 1990 Jul;36(1):27-30. doi: 10.1016/0090-4295(90)80307-9.
A total of 96 patients were treated for localized carcinoma of the prostate using combined Iodine-125 (125I) implantation and external beam radiotherapy. The implant was tailored to deliver 10,000 rad to the periphery of the prostate. A significant incidence of serious late rectal complications was observed. Positive pelvic nodes were found in 28 percent of the patients. Disease-free survival at seven years was 76 percent for those with negative nodes and 46 percent for patients with positive nodes.
共有96例前列腺局限性癌患者接受了碘-125（¹²⁵I）植入与外照射放疗联合治疗。植入治疗旨在向前列腺外周给予10000拉德的剂量。观察到严重晚期直肠并发症的发生率较高。28%的患者发现盆腔淋巴结阳性。淋巴结阴性患者的7年无病生存率为76%，淋巴结阳性患者为46%。
