流行病学干扰。

Epidemiological interference.

机构信息

Johns Hopkins Center for Medical Research, Department of Pathobiology, The Johns Hopkins University, School of Hygiene and Public Health, Baltimore, Maryland 21205, USA.

出版信息

Int J Epidemiol. 1975 Dec;4(4):337-42. doi: 10.1093/ije/4.4.337.

DOI:10.1093/ije/4.4.337

PMID:23682421

Abstract

Wherever intensity of disease transmission (size of virus populations) is great, there will be competition among the different viruses for soil. This competition, which is discussed here as epidemiological interference, was seen in a series of studies in West Bengal, India, and in Nepal. Competition for space led to localization of adenovirus types. Competition at different seasons led to striking variation in seasonal prevalence. Competition for soil and delay in natural immunization led to postponement of infection with childhood diseases to adulthood. Finally, the same phenomenon can explain the early continued high prevalence of poliomyelitis virus in children during the first six years of life in rural West Bengal (12).

摘要

在疾病传播强度（病毒种群规模）较大的地方，不同病毒之间将展开争夺土壤的竞争。这种竞争，在这里被视为流行病学干扰，曾在印度西孟加拉邦和尼泊尔的一系列研究中观察到。对空间的竞争导致腺病毒类型的本地化。不同季节的竞争导致季节性流行率的显著变化。对土壤的竞争和自然免疫的延迟导致儿童期疾病感染推迟到成年期。最后，同样的现象可以解释在农村西孟加拉邦，脊髓灰质炎病毒在生命的头六年持续高流行的早期现象（12）。