Gatsu M V, Puzanova E V, Platonova T L, Gorban' A I
Vestn Oftalmol. 1990 Mar-Apr;106(2):19-21.
The authors analyze the efficacy of He-Ne laser therapy of amblyopia of various origins in 48 children (81 eyes). Group 1 children were not treated at all in order to assess the visual function background fluctuations (absolute controls). Along with He-Ne laser, used in Group 2, a 'placebo', slit lamp with blinking light, was used in Group 3. Vision acuity was assessed with the use of Sivtsev-Golovin's and Orlova's tables and by visocontrastometry in a blind test. Common visometry has shown a reliable and approximately similar improvement of the vision acuity in Groups 2 and 3 patients, whereas visocontrastometry has not detected any changes of visual function in all the 3 groups. These results cast doubt on the true efficacy of He-Ne laser stimulation of visual function, at least in children, and once again demonstrate that such investigations may be carried out only with a reliable ('blind') control and placebo.
作者分析了氦氖激光疗法对48名儿童（81只眼）不同病因弱视的疗效。为评估视觉功能背景波动情况，第1组儿童未接受任何治疗（绝对对照）。第2组使用氦氖激光，第3组除氦氖激光外还使用了“安慰剂”——带闪烁光的裂隙灯。通过Sivtsev-Golovin表和Orlova表以及在盲法测试中使用视觉对比测定法评估视力。常规视力测定显示，第2组和第3组患者的视力有可靠且大致相似的改善，而视觉对比测定法未检测到所有3组视觉功能有任何变化。这些结果使人对氦氖激光刺激视觉功能的真正疗效产生怀疑，至少对儿童是如此，并且再次表明此类研究只能在有可靠（“盲法”）对照和安慰剂的情况下进行。
