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犬非眼部手术后角膜溃疡发生风险因素的评估:14例病例(2009 - 2011年)

Evaluation of risk factors for development of corneal ulcer after nonocular surgery in dogs: 14 cases (2009-2011).

作者信息

Park Young-Woo, Son Won-Gyun, Jeong Man-Bok, Seo Kangmoon, Lee Lyon Y, Lee Inhyung

机构信息

Department of Veterinary Clinical Sciences, BK21 Program and Research Institute for Veterinary Science, College of Veterinary Medicine, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea.

出版信息

J Am Vet Med Assoc. 2013 Jun 1;242(11):1544-8. doi: 10.2460/javma.242.11.1544.

Abstract

OBJECTIVE

To evaluate the prevalence of and risk factors for development of corneal ulcers after nonocular surgery performed with general anesthesia in dogs.

DESIGN

Retrospective case-control study.

ANIMALS

14 dogs with development of corneal ulcers after nonocular surgery and 718 control dogs.

PROCEDURES

Medical records of dogs evaluated at the Veterinary Medical Teaching Hospital of Seoul National University from January 2009 to June 2011 were reviewed for assessment of risk factors for development of corneal ulcers.

RESULTS

Among the 732 reviewed cases, 14 (1.9%) dogs of 6 breeds developed a corneal ulcer after nonocular surgery. Duration of anesthesia was significantly longer in dogs with ulcers than dogs without ulcers. The number of medications received and procedures performed were also significantly higher in dogs with ulcers than dogs without ulcers. Dogs with a small skull (OR, 8.59; 95% confidence interval [CI], 1.04 to 70.90) and dogs that received neurosurgery (OR, 21.12; 95% CI, 5.77 to 77.25) were more susceptible to development of corneal ulcers. Also, postoperative application of a fentanyl patch was a risk factor for development of corneal ulcers (OR, 4.53; 95% CI, 1.05 to 19.60).

CONCLUSIONS AND CLINICAL RELEVANCE

Several risk factors were identified for development of corneal ulcers after nonocular surgery was performed with general anesthesia in dogs. Perioperative eye protection strategies and postoperative ophthalmic examination are needed to reduce the occurrence of corneal ulcers and their progression, especially for high-risk dogs and procedures.

摘要

目的

评估犬全身麻醉下非眼科手术后角膜溃疡的发生率及危险因素。

设计

回顾性病例对照研究。

动物

14只非眼科手术后发生角膜溃疡的犬和718只对照犬。

方法

回顾2009年1月至2011年6月在首尔国立大学兽医学院教学医院评估的犬的病历,以评估角膜溃疡发生的危险因素。

结果

在732例回顾病例中,6个品种的14只(1.9%)犬在非眼科手术后发生了角膜溃疡。溃疡犬的麻醉持续时间显著长于无溃疡犬。溃疡犬接受的药物数量和进行的操作也显著高于无溃疡犬。颅骨小的犬(比值比[OR],8.59;95%置信区间[CI],1.04至70.90)和接受神经外科手术的犬(OR,21.12;95%CI,5.77至77.25)更容易发生角膜溃疡。此外,术后应用芬太尼透皮贴剂是角膜溃疡发生的危险因素(OR,4.53;95%CI,1.05至19.60)。

结论及临床意义

确定了犬全身麻醉下非眼科手术后角膜溃疡发生的几个危险因素。需要采取围手术期眼部保护策略和术后眼科检查,以减少角膜溃疡的发生及其进展,特别是对于高危犬和手术。

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