一个人和一种肽的故事：小 Wylie W. 威尔和促肾上腺皮质释放因子在应激反应中的作用。

The tale of a person and a peptide: Wylie W. Vale Jr. and the role of corticotropin-releasing factor in the stress response.

机构信息

Laboratory of Chemical Neuroanatomy, Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, Av. Prof. Lineu Prestes, 2415, Ed. B-III, Lab 106, 05508-000 São Paulo, SP, Brazil; Center of Neuroscience and Behavior, Institute of Psychology, University of São Paulo, Av. Prof. Mello Moraes, 1721, Bloco C, 05508-030 São Paulo, SP, Brazil.

出版信息

J Chem Neuroanat. 2013 Dec;54:1-4. doi: 10.1016/j.jchemneu.2013.04.005. Epub 2013 May 16.

DOI:10.1016/j.jchemneu.2013.04.005

PMID:23685258

Abstract

The studies reviewed in this article certainly do not constitute the entire body of research conducted by Wylie Vale's group and his collaborators, they might constitute turning points in CRF research. In addition, the studies reviewed here show that, over the course of 31 years (from 1981 to 2012), Wylie tirelessly pursued the answers to fundamental questions regarding CRF. He was a man whose drive never seemed to falter.

摘要

本文回顾的研究当然不能构成 Wylie Vale 小组及其合作者进行的全部研究，它们可能构成了 CRF 研究的转折点。此外，本文回顾的研究表明，在 31 年的时间里（从 1981 年到 2012 年），Wylie 不懈地追求 CRF 基本问题的答案。他是一个似乎从未动摇过的人。