Brandt C M, Boulenc J M, Schott B, Attali P, Fincker J L
Service de Cardiologie, Centre Hospitalo-Universitaire de Strasbourg, France.
Acta Cardiol. 1990;45(3):181-7.
Usefulness of computerized mechanocardiography and echocardiography in the diagnosis of impaired left ventricular diastolic function is shown in a study comparing 17 hypertrophic obstructive cardiomyopathy and 17 hypertensive cardiomyopathy patients to 20 normal subjects. Mechanocardiography allows the evaluation of three different parameters of diastolic function: isovolumic relaxation evaluated by S2a-O or better by t-dr/dt and dr/dt/A2 ratio, left ventricular compliance by the A/H ratio and time of rapid filling. All the parameters are impaired in both pathological populations. Isovolumic relaxation being more depressed in hypertensive cardiomyopathy and duration of rapid filling being prolonged especially in the hypertrophic obstructive cardiomyopathy patients. Although the differences are small indicating only trends computerized mechanocardiography gives some evidence for difference in the alteration of diastolic function in hypertrophic obstructive cardiomyopathy and hypertensive cardiomyopathy.
一项研究对17名肥厚型梗阻性心肌病患者、17名高血压性心肌病患者和20名正常受试者进行了比较,结果显示计算机化机械心动图和超声心动图在诊断左心室舒张功能受损方面具有实用性。机械心动图可评估舒张功能的三个不同参数:通过S2a - O评估等容舒张,或通过t - dr/dt和dr/dt/A2比值评估更佳;通过A/H比值评估左心室顺应性;以及快速充盈时间。在这两种病理人群中,所有参数均受损。等容舒张在高血压性心肌病中更受抑制,快速充盈持续时间延长,尤其是在肥厚型梗阻性心肌病患者中。尽管差异较小,仅表明有趋势,但计算机化机械心动图为肥厚型梗阻性心肌病和高血压性心肌病舒张功能改变的差异提供了一些证据。