Vaskinn Anja, Sundet Kjetil, Ueland Torill, Agartz Ingrid, Melle Ingrid, Andreassen Ole A
KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Oslo, Norway.
J Nerv Ment Dis. 2013 Jun;201(6):445-51. doi: 10.1097/NMD.0b013e31829480c8.
The association between clinical insight and social cognition assessed with an emotion perception task was investigated in schizophrenia (n = 29) and bipolar I disorder (n = 19). Persons with schizophrenia had reduced auditory emotion perception compared with individuals with bipolar I disorder, but levels of visual emotion perception and clinical insight were comparable. In the schizophrenia group, clinical insight was moderately associated with auditory and visual emotion perception (r = 0.36-0.44) and negative symptoms (r = -0.33). Better insight was associated with better social cognition and fewer negative symptoms. In the bipolar I disorder group, clinical insight showed small associations with social cognition (largest r = -0.28) and moderate to large associations with positive, negative, manic, and depressive symptoms. Poorer insight was associated with higher symptom load. Social cognition seems to be of importance for clinical insight in schizophrenia, whereas symptoms are important in bipolar I disorder.
我们在精神分裂症患者（n = 29）和双相I型障碍患者（n = 19）中，研究了通过情感感知任务评估的临床洞察力与社会认知之间的关联。与双相I型障碍患者相比，精神分裂症患者的听觉情感感知能力下降，但视觉情感感知水平和临床洞察力相当。在精神分裂症组中，临床洞察力与听觉和视觉情感感知（r = 0.36 - 0.44）以及阴性症状（r = -0.33）呈中度相关。更好的洞察力与更好的社会认知和更少的阴性症状相关。在双相I型障碍组中，临床洞察力与社会认知呈小幅度关联（最大r = -0.28），与阳性、阴性、躁狂和抑郁症状呈中度至大幅度关联。洞察力较差与更高的症状负荷相关。社会认知似乎对精神分裂症的临床洞察力很重要，而症状在双相I型障碍中很重要。
