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Successful treatment of systemic blastomycosis with high-dose ketoconazole in a renal transplant recipient.

作者信息

Hii J H, Legault L, DeVeber G, Vas S I

机构信息

Department of Microbiology, Toronto Hospital, Ontario, Canada.

出版信息

Am J Kidney Dis. 1990 Jun;15(6):595-7. doi: 10.1016/s0272-6386(12)80532-4.

DOI:10.1016/s0272-6386(12)80532-4
PMID:2368699
Abstract

A case of disseminated blastomycosis in a male renal transplant recipient is presented. Discontinuation of immunosuppressive therapy and treatment with high-dose ketoconazole was successful in treating the patient's cutaneous and pulmonary disease initially. Ketoconazole was discontinued after 12 months of chronic therapy, but 2 weeks after discontinuation, blastomycosis recurred. High-dose ketoconazole was again effective; the patient remains asymptomatic presently on chronic suppressive therapy with ketoconazole.

摘要

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Clinical Characteristics and Outcomes of Endemic Mycoses After Solid Organ Transplantation: A Comprehensive Review.实体器官移植后地方性真菌病的临床特征与转归:一项综述
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2
Infections in solid-organ transplant recipients.实体器官移植受者的感染
Clin Microbiol Rev. 1997 Jan;10(1):86-124. doi: 10.1128/CMR.10.1.86.