Chen Chen, Liu Xiaojia, Pan Suyue, Wu Xiaoqin, Wu Jibao
Department of Neurology, Southern Medical University, Guangzhou, China.
Nan Fang Yi Ke Da Xue Xue Bao. 2013 May;33(5):713-8.
To analyze the neurolinguistic features of a Chinese patient with pure alexia in acute and convalescent stages.
We assessed the reading and writing abilities of the patient with the Aphasia Battery of Chinese (ABC), the reading examination of Chinese characters (1999, Lin) and the Chinese agraphia battery (CAB).
In the ABC examination in the acute phase, the patient performed well in oral expression and comprehension, and the prominent linguistic abnormalities were alexia and merging agraphia; in the convalescent phase, the recovery of alexia was better than that of agraphia. In reading examination of Chinese characters, shape errors were the main reading disorders in the acute phase with a few semantic errors, regularization errors and mistakes in pronunciation, but only shape errors reappeared in the recovery period. CAB examination showed impairment of writing for pictures and dictation abilities in the recovery period but recovery of other writing abilities. The writing disorder was manifested as aphasic agraphia, with obvious dysorthography and lexical errors; the patient was capable of spontaneous writing only after spontaneous speech, and was able to read the written words.
The linguistic components of the Chinese patient with pure alexia showed different patterns of damage and recovery, suggesting the difference in their respective neuropsychological pathways.
分析一名中国纯失读症患者急性期和恢复期的神经语言学特征。
我们使用中国失语症成套测验（ABC）、汉字阅读测验（1999年，林）和汉语失写症成套测验（CAB）对该患者的读写能力进行评估。
在急性期的ABC测验中，患者口语表达和理解能力良好，突出的语言异常为失读和合并性失写；在恢复期，失读的恢复情况优于失写。在汉字阅读测验中，急性期主要的阅读障碍是字形错误，伴有少量语义错误、正字法错误和发音错误，但恢复期仅再次出现字形错误。CAB测验显示恢复期图片书写和听写能力受损，但其他书写能力恢复。书写障碍表现为失语性失写，有明显的拼写错误和词汇错误；患者仅在自发言语后才能自发书写，且能读出所写的单词。
中国纯失读症患者的语言成分表现出不同的损伤和恢复模式，提示其各自神经心理通路存在差异。
