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[胃食管反流的家族性形式]

[Familial forms of gastro-esophageal reflux].

作者信息

de Boissieu D, de Montis G, Badoual J

机构信息

Département de Pédiatrie, Hôpital Saint-Vincent-de-Paul, Paris.

出版信息

Ann Pediatr (Paris). 1990 Apr;37(4):221-5.

PMID:2369044
Abstract

Gastroesophageal reflux is a common disorder that can be responsible for respiratory disease and is not considered as an inherited condition. We report five families with several affected members. Other familial cases have been published and some authors have suggested that transmission occurs on an autosomal dominant basis. Only prospective studies could determine whether GER is an inherited disorder, but at present their feasibility is limited since currently available diagnostic investigations are not suitable for screening.

摘要

胃食管反流是一种常见疾病,可导致呼吸系统疾病,且不被视为遗传性疾病。我们报告了五个有多名受累成员的家族。其他家族性病例也有报道,一些作者认为其遗传方式为常染色体显性遗传。只有前瞻性研究才能确定胃食管反流是否为遗传性疾病,但目前其可行性有限,因为现有的诊断检查方法不适合用于筛查。

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