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[新生儿及婴儿的心脏肿瘤。附5例报告]

[Tumors of the heart in newborn infants and infants. Apropos of 5 cases].

作者信息

Roux P M, Ghorayeb G, Touati G, Vouhe P, Fermont L, Baillot-Vernant F, Leca F, Neveux J Y

机构信息

Service de Chirurgie Cardio-Vasculaire et Thoracique, Hôpital, Laennec, Paris.

出版信息

Ann Pediatr (Paris). 1990 May;37(5):323-6.

PMID:2369049
Abstract

Between February 1985 and March 1987, 5 children underwent resection of primary cardiac neoplasms, 3 of them in the first days of life and 2 before the age of 6 months. Routine echocardiographic follow-up of pregnancies allowed detection of cardiac tumors in 2 foetuses 30 and 36 weeks old. In 3 children the diagnosis was suspected by the discovery of cardiac murmur or congestive heart failure. The first case was a hemangioma, originating from outside the left ventricular wall, and was resected without cardiopulmonary bypass (CPBP). The other case was a pseudomyxoma, spreading extensively in to the right atrium. The third case was a rhabdomyoma arising from the pulmonary infundibulum with clinical manifestations of tuberous sclerosis. The last two patients had intraseptal lesions, just above the aortic valve; complete resection was therefore impossible, particularly in one patient with multiple tumors. There was one death related to congestive heart failure. The remaining four survivors were followed up for an average of 18.4 months (+/- 12.9) and all were in functional class I. Echocardiographic follow-up showed evidence of a residual subaortic lesion in one asymptomatic patient.

摘要

1985年2月至1987年3月期间,5名儿童接受了原发性心脏肿瘤切除术,其中3名在出生后的头几天接受手术,2名在6个月龄前接受手术。通过对孕妇进行常规超声心动图随访,在2名分别为30周和36周龄的胎儿中发现了心脏肿瘤。在3名儿童中,通过发现心脏杂音或充血性心力衰竭怀疑患有该病。第一例是血管瘤,起源于左心室壁外,在未进行体外循环(CPBP)的情况下进行了切除。另一例是假黏液瘤,广泛扩散至右心房。第三例是起源于肺动脉漏斗部的横纹肌瘤,伴有结节性硬化症的临床表现。最后两名患者在主动脉瓣上方有室间隔内病变;因此无法进行完全切除,尤其是其中一名患有多发性肿瘤的患者。有1例死亡与充血性心力衰竭有关。其余4名幸存者平均随访了18.4个月(±12.9),所有患者的心功能均为I级。超声心动图随访显示,1例无症状患者有残余主动脉下病变。

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