Fauchier J P, Cosnay P, Babuty D, Placente M, Estepo J
Service de Cardiologie B, Hôpital Trousseau, Tours.
Ann Cardiol Angeiol (Paris). 1990 May;39(5):287-94.
The exploration of 113 cases of myocardiopathy (69 cases of dilated myocardiopathy (DMC) and 44 of hypertrophic myocardiopathy (HMC) by a 24-hour Holter recording, exercise tests, recording of surface-delayed ventricular potentials (DVPs) and forced right ventricular stimulation (PVS), revealed an arrhythmogenic potential in both forms of this disorder. In cases of DMC, ventricular arrhythmias were common (81% of cases), frequently recurrent and may constitute one sign of the disease, although they are fairly independent of hemodynamic changes. The presence of DVPs in cases of DMC (25% of cases) was significantly correlated with ventricular extra-systole greater than or equal to grade 3 on the lown scale revealed by the Holter with induction of tachycardia or ventricular fibrillation in response to PVS. Ventricular arrhythmia is less common in HMC (57%). DVPs were rare, and spontaneous or induced ventricular arrhythmia appeared to be more closely correlated with syncope than with any other hemodynamic factor. This study of the arrhythmogenic potential therefore appears to be necessary in myocardiopathy in order to obtain a better definition of the prognostic risk.
通过24小时动态心电图记录、运动试验、体表心室晚电位（DVP）记录和右心室起搏（PVS）对113例心肌病患者（69例扩张型心肌病（DMC）和44例肥厚型心肌病（HMC））进行的探索显示，这两种形式的疾病均有致心律失常的可能性。在DMC病例中，室性心律失常很常见（81%的病例），频繁复发，可能是该疾病的一个体征，尽管它们与血流动力学变化相当独立。DMC病例中DVP的存在（25%的病例）与动态心电图显示的洛恩分级中≥3级室性早搏显著相关，并伴有PVS诱发的心动过速或心室颤动。室性心律失常在HMC中较少见（57%）。DVP很少见，自发或诱发的室性心律失常似乎与晕厥的相关性比与任何其他血流动力学因素的相关性更强。因此，对心肌病的致心律失常可能性进行这项研究似乎很有必要，以便更好地界定预后风险。
