Zhu Xiong-zeng
Department of Pathology, Fudan University Cancer Center,Shanhai, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Jan;16(1):12-4.
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a group of tumors derived from diffuse neuroendocrine cells of the digestive system. All GEP-NEN shave potential malignancy. According to the WHO classification (2010), GEP-NENs can be divided into well differentiated neuroendocrine tumor (NET) and poorly differentiated neuroendocrine carcinoma (NEC). GEP-NEN scan be grouped into three grades: G1 , G2 and G3. The new WHO classification unifies the diagnostic terms and avoids the confusion of the nomenclature and classification of GEP-NENs,which is the foundation of clinical treatment and prognostic estimation.
胃肠胰神经内分泌肿瘤（GEP-NENs）是一组起源于消化系统弥漫性神经内分泌细胞的肿瘤。所有GEP-NENs都有潜在的恶性倾向。根据世界卫生组织（WHO）2010年分类，GEP-NENs可分为高分化神经内分泌肿瘤（NET）和低分化神经内分泌癌（NEC）。GEP-NENs可分为G1、G2和G3三级。WHO新分类统一了诊断术语，避免了GEP-NENs命名和分类的混乱，这是临床治疗和预后评估的基础。
