Shimizu K, Abe M, Tsukada K
Department of Pathological Biochemistry, Medical Research Institute, Tokyo Medical and Dental University, Japan.
Biochem Int. 1990;20(6):1105-10.
Betaine-homocysteine- and S-adenosylmethionine-homocysteine-methyltransferases which catalyze synthesis of methionine from homocysteine are absent in tumor cells such as mouse Ehrlich ascites tumor cells and rat hepatoma AH-109A ascites cells.
催化从同型半胱氨酸合成甲硫氨酸的甜菜碱 - 同型半胱氨酸和S - 腺苷甲硫氨酸 - 同型半胱氨酸甲基转移酶在肿瘤细胞中不存在，如小鼠艾氏腹水瘤细胞和大鼠肝癌AH - 109A腹水细胞。
