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钝性脾损伤非手术治疗患者的共识策略:一项 Delphi 研究。

Consensus strategies for the nonoperative management of patients with blunt splenic injury: a Delphi study.

机构信息

Trauma Unit, Academic Medical Center, Amsterdam, The Netherlands.

出版信息

J Trauma Acute Care Surg. 2013 Jun;74(6):1567-74. doi: 10.1097/TA.0b013e3182921627.

Abstract

BACKGROUND

Nonoperative management is the standard of care in hemodynamically stable patients with blunt splenic injury. However, a number of issues regarding the management of these patients are still unresolved. The aim of this study was to reach consensus among experts concerning optimal treatment and follow-up strategies.

METHODS

The Delphi method was used to reach consensus among 30 expert trauma surgeons and interventional radiologists from around the world. An online survey was used in the two study rounds. Consensus was defined as an agreement of 80% or greater.

RESULTS

Response rates of the first and second rounds were 90% and 80%, respectively. Consensus was reached for 43% of the (sub)questions. The American Association for the Surgery of Trauma organ injury scale for grading splenic injury is used by 93% of the experts. In hemodynamically stable patients, observation or splenic artery embolization (SAE) can be applied in the presence of a small or no hemoperitoneum combined with an intraparenchymal contrast extravasation or no contrast extravasation, regardless of the presence of an arteriovenous (AV) fistula/pseudoaneurysm. Hemodynamic instability is an indication for operative management, irrespective of computed tomographic characteristics and grade of splenic injury (≥82% of the experts). Operative management is also indicated in the presence of associated intra-abdominal injuries and/or the need for five or more packed red blood cell transfusions (22 of 27 experts, 82%). Recommended time span to start SAE in a stable patient with an intraparenchymal contrast extravasation is 60 minutes (19 of 24 experts). Patients should be admitted 1 to 3 days to a monitored setting (27 of 27 experts, 100%). Serial hemoglobin checks are performed by all experts, every 4 to 6 hours in the first 24 hours and once or twice a day after that (21 of 24 experts, 88%), in nonoperative management as well as after SAE. Routine postdischarge imaging is not indicated (21 of 24 experts, 88%).

CONCLUSION

Although treatment should always be adjusted to the specific patient, the results of this study may serve as general guidelines.

摘要

背景

在血流动力学稳定的钝性脾损伤患者中,非手术治疗是标准的治疗方法。然而,对于这些患者的管理仍存在许多问题尚未解决。本研究的目的是在全球范围内的 30 名创伤外科专家和介入放射学家之间达成关于最佳治疗和随访策略的共识。

方法

采用德尔菲法对来自世界各地的 30 名创伤外科专家和介入放射学家进行在线调查,以达成共识。两轮研究的回复率分别为 90%和 80%。对于 43%的(子)问题达成了共识。93%的专家使用美国外科创伤协会的器官损伤分级标准来分级脾损伤。对于血流动力学稳定、腹膜小量积血或无积血伴实质内对比剂外渗或无对比剂外渗的患者,无论是否存在动静脉(AV)瘘/假性动脉瘤,均可采用观察或脾动脉栓塞(SAE)。无论 CT 特征和脾损伤程度如何(≥82%的专家),血流动力学不稳定均为手术治疗的指征。对于合并腹腔内损伤和/或需要 5 个或更多单位浓缩红细胞输注的患者(27 名专家中的 22 名,82%)也需要手术治疗。对于实质内对比剂外渗的稳定患者,开始 SAE 的建议时间窗为 60 分钟(24 名专家中的 19 名)。所有专家建议患者在稳定后住院 1 至 3 天,入住监测病房(27 名专家,100%)。所有专家在非手术治疗和 SAE 后每 4 至 6 小时监测血红蛋白,前 24 小时监测 1 至 2 次/天(24 名专家中的 21 名,88%)。出院后无需常规进行影像学检查(24 名专家中的 21 名,88%)。

结论

尽管治疗应始终根据患者的具体情况进行调整,但本研究的结果可以作为一般指南。

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