Department of Clinical and Experimental Medicine, University Hospital, University of Parma, Padiglione Barbieri, 3° piano, Via Gramsci, 14, 43126 Parma, Italy.
Neurol Sci. 2013 May;34 Suppl 1:S57-60. doi: 10.1007/s10072-013-1377-x.
Once migraine becomes chronic and has transformed into a form of headache that occurs daily or almost, the treatment options available are few and complex. This makes it important to take action before this point is reached, using all the measures that can be obtained from our current knowledge of chronic migraine (or transformed migraine) on the one hand, and on the potential factors of chronification (or transformation) on the other. Therefore, in order to reduce the risk of migraine chronification, it would appear important to: (a) administer suitable preventive treatments for subjects who have been suffering from migraines ≥4 days a month for ≥3 months; (b) take special care not to overuse symptomatic medications, particularly when they contain substances with a sedative effect; and (c) investigate the concomitant presence of depression, hypertension and excess weight and administer appropriate treatment when present.
一旦偏头痛变成慢性的、每天或几乎每天都发作的头痛形式，那么可用的治疗选择就很少且复杂。这就是为什么在到达这一点之前采取行动很重要，一方面利用我们目前对慢性偏头痛（或转化性偏头痛）的所有知识，另一方面利用潜在的慢性化（或转化）因素。因此，为了降低偏头痛慢性化的风险，似乎很重要的是：(a) 对每月偏头痛发作≥4 天且持续≥3 个月的患者进行适当的预防性治疗；(b) 特别注意不要过度使用对症药物，特别是当它们含有镇静作用的物质时；(c) 调查是否存在抑郁、高血压和超重，并在存在时进行适当治疗。
