Department of Surgical Oncology, Catharina Hospital Eindhoven, P.O. Box 1350, 5602, ZA Eindhoven, The Netherlands.
Int J Colorectal Dis. 2013 Sep;28(9):1307-10. doi: 10.1007/s00384-013-1714-9. Epub 2013 May 22.
Mucinous appendiceal tumours were described already 180 years ago, but reliable data on the incidence of these tumours are sparse. The clinical importance of these tumours is increasing since they are now identified as the most common site of origin for pseudomyxoma peritonei (PMP), which is currently recognised as a treatable condition.
Data on the incidence of mucinous appendiceal tumours were retrieved from the Eindhoven Cancer Registry, which collects data on all patients with newly diagnosed cancer in a large part of the southern Netherlands that comprises about 2.3 million inhabitants. From 1980 to 2010, all cases of primary adenocarcinomas of the appendix were included.
From 1980 to 2010, a mucinous adenocarcinoma was diagnosed in 78 patients being 48 % of all cases of appendiceal adenocarcinoma diagnosed during this period (n = 164). The incidence increased during the study period from 0.6 to 1.9 per 1,000,000 person-years for women and from 0.4 to 1.0 per 1,000,000 person-years for men.
The reported incidence of mucinous adenocarcinomas of the appendix shows an increasing trend. This is probably mainly explained by the increased awareness of this tumour and its relation with PMP, and better registration of this specific diagnosis.
黏液性阑尾肿瘤早在 180 年前就已被描述，但关于这些肿瘤发病率的可靠数据却很少。由于这些肿瘤现在被认为是腹膜假性黏液瘤（PMP）最常见的起源部位，其临床重要性正在增加，而 PMP 目前被认为是一种可治疗的疾病。
从埃因霍温癌症登记处检索了黏液性阑尾肿瘤的发病率数据，该登记处收集了荷兰南部大部分地区（约 230 万居民）所有新发癌症患者的数据。从 1980 年到 2010 年，所有原发性阑尾腺癌病例均被纳入研究。
在 1980 年至 2010 年间，78 例患者被诊断为黏液性腺癌，占同期诊断的所有阑尾腺癌病例（n=164）的 48%。在研究期间，女性的发病率从 0.6 增至 1.9/100 万人年，男性的发病率从 0.4 增至 1.0/100 万人年。
报告的阑尾黏液性腺癌发病率呈上升趋势。这可能主要归因于对这种肿瘤及其与 PMP 的关系的认识提高，以及对这种特定诊断的更好登记。
