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[普拉西多角膜地形图联合光学生物测量——初步结果]

[Placido topography combined with optical biometry--first results].

作者信息

Oltrup T, Leitritz M A, Voykov B, Bende T

机构信息

Stiftungslabor für Grundlagenforschung, Universitäts-Augenklinik Tübingen, Schleichstrasse 12, Tübingen.

出版信息

Klin Monbl Augenheilkd. 2013 May;230(5):519-23. doi: 10.1055/s-0032-1328499. Epub 2013 May 21.

DOI:10.1055/s-0032-1328499
PMID:23695849
Abstract

INTRODUCTION

Optical biometry for calculation of intraocular lenses (IOL) was introduced by Zeiss with the IOLMaster. A newly developed system combines both video topography and optical coherence biometry (BioTop). This allows not only the conventional calculation of IOLs but also enables the design of customised IOLs based on ray-tracing. This paper presents first results regarding the axial length measurement of the new device compared to the IOLMaster.

METHODS

The accuracy of the combination system (BioTop) is proven by a well known reference (20,010 ± 0,004) mm. To compare the new system BioTop with the IOLMaster (two different versions 3 and 5) are used. Measurements are taken at the known reference and at 47 eyes with different stages of cataract.

RESULTS

The mean geometrical length for 50 measurements of the known reference was AL = (20.011 ± 0.001) mm. For the standard conditions (5 single measurements) the length results in AL = (20.010 ± 0.001) mm. For the IOLMaster these numbers are: AL = (20.00 ± 0,01) mm for version 3 and AL = (20.02 ± 0.01) mm for version 5 also based on 5 single measurements. The measurable axial lengths for the cataract eyes (43 for IOLMaster and 37 for the BioTop) show a mean difference of - 0.015 mm for the two systems. One outlier was detected.

CONCLUSION

The measurements of the know reference showed a high accuracy for all systems. The differences in length measurements on the cataract eyes are clinically not relevant. The combination of topography and optical biometry allows new options for calculations of intraocular lenses.

摘要

引言

蔡司公司推出的IOLMaster实现了用于计算人工晶状体(IOL)的光学生物测量。一种新开发的系统将视频地形图和光学相干生物测量(BioTop)相结合。这不仅可以进行传统的人工晶状体计算,还能够基于光线追踪设计定制的人工晶状体。本文展示了与IOLMaster相比,该新设备轴向长度测量的初步结果。

方法

通过一个知名参考值(20.010±0.004)mm验证了组合系统(BioTop)的准确性。为了将新系统BioTop与IOLMaster(两个不同版本3和5)进行比较,在已知参考值处以及47只处于不同白内障阶段的眼睛上进行测量。

结果

对已知参考值进行50次测量的平均几何长度为AL =(20.011±0.001)mm。在标准条件下(5次单次测量),长度结果为AL =(20.010±0.001)mm。对于IOLMaster,基于5次单次测量,版本3的这些数值为:AL =(20.00±0.01)mm,版本5的数值为:AL =(20.02±0.01)mm。对于白内障眼睛的可测量轴向长度(IOLMaster为43只,BioTop为37只),两个系统的平均差异为 - 0.015 mm。检测到一个异常值。

结论

对已知参考值的测量表明所有系统都具有高精度。白内障眼睛长度测量的差异在临床上不具有相关性。地形图和光学生物测量的结合为人工晶状体的计算提供了新的选择。

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