异基因骨髓移植后发生重症肌无力：1例新病例报告及发病机制探讨
Myasthenia gravis after allogeneic bone marrow transplantation: report of a new case and pathogenetic considerations.
作者信息
Grau J M, Casademont J, Monforte R, Marín P, Grañena A, Rozman C, Urbano-Márquez A
机构信息
Muscle Research Unit, Hospital Clinic i Provincial, Barcelona, Spain.
出版信息
Bone Marrow Transplant. 1990 Jun;5(6):435-7.
PMID:2369684
Abstract
A 21-year-old caucasian man with T acute lymphoblastic leukemia underwent a bone marrow transplantation (BMT) and developed classic myasthenia gravis (MG) 46 months later. The association of almost all published cases with HLA B35 is discussed, as are the clinical aspects suggesting that BMT survivors are at risk for developing MG as part of the spectrum of chronic graft-versus-host disease.
摘要
一名患有T急性淋巴细胞白血病的21岁白种男性接受了骨髓移植（BMT），46个月后患上了典型的重症肌无力（MG）。本文讨论了几乎所有已发表病例与HLA B35的关联，以及一些临床方面的情况，这些情况表明骨髓移植幸存者有患重症肌无力的风险，这是慢性移植物抗宿主病谱系的一部分。
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