El-Bahnasawy Mamdouh, Megahed Laila Abdel-Mawla, Abdalla Saleh Hala Ahmed, Morsy Tosson A
The Military Medical Services For Preventive Medicine, Ain Shams University, Cairo 11566, Egypt.
J Egypt Soc Parasitol. 2013 Apr;43(1):41-56. doi: 10.12816/0006366.
The Rift Valley fever (RVF) is a neglected, emerging, mosquito-borne disease with severe negative impact on human and animal health and economy. RVF is caused by RVF virus of the family of Bunyaviridae, genus Phlebovirus. RVF is an acute, febrile disease affecting humans and a wide range of animals. The virus is trans-mitted through the bites from mosquitoes and exposure to viremic blood, body fluids, or contact with tissues of infected animals or by inhaling natural virus aerosols, also possibly by consumption of infected unpasteurized milk. The RVF-virus replicate at the site introduction and in local lymphatic followed by viremia and spread to other organs as the liver and central nervous system, causing the hepatic necrosis and eosinophilia cytoplasmic degeneration. The main signs and symptoms are fever, headache, myalgia, arthralgia, photophobia, bradycardia, conjunctivitis and flushing face. Main complications include jaundice, hemorrhagic, meningoencephalitis and retinal lesions. Generally speaking, in the 21st Century, the vector-borne infectious diseases, was accepted as the disaster issues with the considerable significant morbidity and mortality. These facts should be considered by the public health, veterinary and agricultural authorities
裂谷热是一种被忽视的、新出现的、由蚊子传播的疾病，对人类、动物健康及经济造成严重负面影响。裂谷热由布尼亚病毒科白蛉病毒属的裂谷热病毒引起。裂谷热是一种影响人类和多种动物的急性发热性疾病。该病毒通过蚊子叮咬、接触病毒血症血液、体液、接触受感染动物的组织或吸入天然病毒气溶胶传播，也可能通过食用受感染的未杀菌牛奶传播。裂谷热病毒在引入部位和局部淋巴结复制，随后发生病毒血症并扩散至肝脏和中枢神经系统等其他器官，导致肝坏死和嗜酸性粒细胞胞质变性。主要症状和体征包括发热、头痛、肌痛、关节痛、畏光、心动过缓、结膜炎和面部潮红。主要并发症包括黄疸、出血、脑膜脑炎和视网膜病变。一般来说，在21世纪，媒介传播的传染病被公认为是具有相当高发病率和死亡率的灾害性问题。公共卫生、兽医和农业当局应考虑这些事实
