Timmermans A Jacqueline, Brandsma Dieta, Smeele Ludi E, Rosingh Andert W, van den Brekel Michiel W M, Lohuis Peter J F M
Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
Ann Otol Rhinol Laryngol. 2013 Apr;122(4):273-6. doi: 10.1177/000348941312200410.
Two patients with recurrent carcinoma of the posterior pharyngeal wall, previously treated with carbon dioxide (CO2) laser excision and (chemo)radiotherapy, presented with neck pain due to cervical osteomyelitis. In one patient this led to cervical spine instability, for which a haloframe was applied. Our working hypothesis was that cervical osteomyelitis was caused by an infected wound bed induced by CO2 laser excision of the tumor in the already vascular-compromised area of the irradiated posterior pharyngeal wall. We discuss the risks of leaving a wound for secondary granulation after CO2 laser excision of the posterior pharyngeal wall and prophylactic antibiotic treatment.
两名后咽壁复发性癌患者，之前接受过二氧化碳（CO2）激光切除和（化疗）放疗，因颈椎骨髓炎出现颈部疼痛。其中一名患者出现颈椎不稳，为此使用了头环固定架。我们的工作假设是，颈椎骨髓炎是由在已接受放疗的后咽壁血管受损区域进行CO2激光切除肿瘤所导致的感染创面引起的。我们讨论了后咽壁CO2激光切除术后留下创面进行二期肉芽形成的风险以及预防性抗生素治疗。
