Giakoumis Matrona, Ryan Jay D, Jani Jigna
Department of Podiatry, DeKalb Medical Center, Decatur, GA 30033, USA.
J Am Podiatr Med Assoc. 2013 May-Jun;103(3):218-22. doi: 10.7547/1030218.
The present study was conducted in an attempt to obtain consistent similarities among histologic findings of surgically excised neuromas. Secondly, we looked for a correlation between the presence of a neuroma with certain comorbidities.
A total of 22 specimens with a preoperative diagnosis of Morton's neuroma were sent to the pathology laboratory, and evaluation was performed by a single pathologist.
Degenerative changes were seen in 59% of the specimens. Patient age showed trends toward affecting nerve fibrosis, nerve diameter, vessel obstruction, and degenerative changes. The most frequent comorbidity was hypertension, seen in 44% of the participants.
Significant histologic similarities among results were not seen; however, certain trends were discovered. Degenerative changes were appreciated in most specimens. Definite histologic findings of neuroma recur, but difficulty in consistent reproducibility may be related to factors such as age, sex, and comorbidities.
本研究旨在获取手术切除的神经瘤组织学结果之间的一致相似性。其次，我们寻找神经瘤的存在与某些合并症之间的相关性。
总共22例术前诊断为莫顿神经瘤的标本被送至病理实验室，由一名病理学家进行评估。
59%的标本出现退行性改变。患者年龄显示出影响神经纤维化、神经直径、血管阻塞和退行性改变的趋势。最常见的合并症是高血压，44%的参与者患有高血压。
结果之间未发现显著的组织学相似性；然而，发现了某些趋势。大多数标本出现了退行性改变。神经瘤明确的组织学结果会复发，但难以一致再现可能与年龄、性别和合并症等因素有关。
